Tag Archives: Focus

Side Effects of Extensively Prescribed Antipsychotic Drugs the Focus of $1.2M NIH Grant Awarded to University of New England Researcher Karen Houseknecht

Posted on by


Portland, Maine (PRWEB) June 28, 2013

The U.S. National Institutes of Well being (NIH) reports that as diagnoses of mental overall health disorders have risen amongst kids more than the past two decades, far more young children have been prescribed antipsychotic drugs, often off label. Second-generation antipsychotics (SGAs) are broadly prescribed to adults and children for the remedy of schizophrenia, bipolar disorder, focus deficit disorder and other conditions. These drugs are also increasingly being prescribed off-label to treat a number of other ailments, like attention-deficit/hyperactivity disorder (ADHD), especially among poor youngsters[1], each nationally and in Maine[2], as an alternative to stimulants such as Ritalin, which are FDA-authorized for the remedy of ADHD.

&#13

Karen L. Houseknecht, Ph.D., professor of pharmacology at the University of New England (UNE) Department of Pharmaceutical Sciences, research the potentially severe and lasting side effects of SGAs, such as kind 2 diabetes, obesity, and bone loss. She has just received a four-year, $ 1.2 million grant from the National Institutes of Well being to additional study the effects of SGA drugs on bone biology, and to determine the underlying mechanisms by which these drugs lead to bone loss, with the ultimate goals of informing the discovery and improvement of safer antipsychotic medicines and identifying co-therapies that will decrease side effects in individuals presently taking SGA medications.

&#13

Houseknechts investigation focuses on the underlying pharmacological mechanisms of SGA drugs, including the mostly extensively prescribed drug, risperidone. In her prior operate, Houseknecht has published that SGA drugs such as olanzapine and clozapine can induce serious insulin resistance following a single clinically relevant dose, consistent with the clinical findings that SGA drugs result in significant weight achieve and diabetes in many individuals. Far more recently, clinical reports indicate improved risk of fractures in sufferers taking SGA drugs, which includes risperidone. Final year, Houseknecht and her collaborators at Maine Healthcare Study Institute published operate displaying that risperidone remedy of adolescent mice outcomes in significant bone loss, indicating significant threat for adolescent patients being administered this medication.

&#13

She states, Although effective for the remedy of significant mental illness such as schizophrenia and bipolar disorder, SGAs are really powerful drugs with critical side effects that can have lasting wellness consequences for millions of adults and youngsters. Our investigation might much better inform physicians and parents about the possible side effects associated to these drugs, and probably lead to identification of co-therapies to counteract these deleterious effects.

&#13

Houseknechts investigation, Trabecular bone loss soon after administration of the second-generation antipsychotic risperidone is independent of weight obtain, is published in the journal Bone and co-authored with Maine researchers Clifford Rosen, M.D., and Katherine Motyl, Ph.D., from the Maine Healthcare Center Research Institute. Rosen is director of the Center for Clinical and Translational Study at Maine Health-related Center, and an expert on bone osteoporosis.

&#13

The University of New England (UNE) is an innovative health sciences university grounded in the liberal arts, with two distinctive coastal Maine campuses and distinctive study abroad opportunities. UNE has internationally recognized scholars in the sciences, overall health, medicine and humanities provides far more than 40 undergraduate, graduate and expert degree applications and is residence to Maines only healthcare college. It is 1 of a handful of private universities with a complete well being education mission which includes medicine, pharmacy, dental medicine, nursing and an array of allied well being professions. UNE’s interprofessional education initiatives prepare future healthcare experts to practice complete and collaborative team-based care. Each graduate and undergraduate students engage in analysis and scholarship alongside devoted faculty who are committed to their academic and specialist accomplishment.

&#13

[1] Wellness Serv Res. 2012 Oct47(5):1836-60. doi: 10.1111/j.1475-6773.2012.01461.x. Epub 2012 Sep 4:The partnership between mental overall health diagnosis and treatment with second-generation antipsychotics over time: a national study of U.S. Medicaid-enrolled young children.:Matone M, Localio R, Huang YS, dosReis S, Feudtner C, Rubin D.

&#13

2 Antipsychotic Medication Use in medicaid Young children and Adolescents: Report and resource guide from a 16-state study. MMDLN/Rutgers CERTs Publication #1. July 2010. Distributed by Rugers CERTs http://rci.rutgers.edu/~cseap/MMDLNAPKIDS.html

&#13
&#13
&#13
&#13
&#13

Niche Focus Group Predicts Sunbelt States Most Most likely to Rebound 1st in Genuine Estate Downturn

Posted on by


Phoenix, AZ (PRWEB) June 11, 2009

In light of the radical changes recently in the Real Estate market over the past two years, Americas entrepreneurs uncover opportunity to turn market place crisis to their advantage.

&#13

Businesses of every single type are in search of to maximize ways to advantage from opportunities produced from chaos. Everything from loan modifications to acquiring foreclosed homes, capitalists are playing their roles to assist stimulate the American economy and at the very same time justify America as the land of chance.

&#13

Troy Bohlke, CEO of Niche Concentrate Group, an Marketing firm specializing in making Genuine Estate investment packages for Actual Estate Funds states, I am amazed with the good attitudes of these aggressive entrepreneurs. They see treasures in this marketplace. It is inspiring. Following carrying out substantial study needed to develop our clients investment packages, I learned speedily that when the market at bottom is exactly when our consumers make excellent buys. Massive profits are created accessible to these investors with liquidity, timing, and executing a effectively made program. Our Fund consumers are purchasing up as a lot real estate as they can get their hands on.

&#13

Billionaire genuine estate mogul, Donald Trump agrees that this is the best time to buy. Its an amazing time to purchase, Trump stated. This is the greatest time Ive ever noticed to buy each real estate and almost certainly other things. This is 1 of the great possibilities.

&#13

The Current Predicament&#13

According to the Metropolitan Foreclosure Market place Report for Q1 of 2009, California, Florida, Nevada and Arizona accounted for the 26 highest foreclosure rates amongst metro areas with a population of 200,000 or much more. The metro areas with the highest levels of foreclosure activity in the initial quarter of 2009 paint a picture of concentrated issues in a reasonably tiny number of challenging hit locations, stated James J. Saccacio, chief executive officer of RealtyTrac, a California based business that tracks foreclosure filings.

&#13

For example, one in every single 43 Nevada households received a foreclosure filing in the course of the second quarter, the highest foreclosure price amongst the states and nearly four instances the national average. Foreclosure filings had been reported on 24,657 Nevada properties for the duration of the quarter, up 26 percent from the previous quarter and up 147 percent from the very first quarter of 2007.

&#13

Foreclosure filings have been reported on 202,599 California properties during the second quarter, the highest total among the states and a rate of a single in each and every 65 households the nations second highest state foreclosure price. Foreclosure activity in California enhanced 19 percent from the preceding quarter and was practically three times the level reported in the second quarter of 2007.

&#13

In spite of these staggering statistics, Bohlke and his group at Niche Concentrate Group are booming with enterprise from optimistic True Estate investors pooling their income collectively in funds. Our investors and clients are convinced that the Sunbelt states, although the hardest hit, are also the most likely to bounce back the quickest on the true estate upswing.

&#13

Sales activity appears to be rising in some of the hardest hit markets as home costs have fallen to levels that are eye-catching to very first-time homebuyers and investors, Stated Saccacio of Realtytrac. 45% of the transactions were distressed sales, foreclosures and quick sales, which lead to the decline in the median price. Nonetheless, these cost drops lead to the biggest obtain in sales volume for the fourth quarter especially in the Sunbelt states Nevada, up 133.7 %, followed by California, rose 84.7 %, Arizona, up 42.6 % and Florida with a 12.five percent enhance.

&#13

Bohlke states that in adapting to these trends, that his firm has been packaging offerings for Actual Estate Funds each large and small. We discover that the hottest target seems to be foreclosed single loved ones homes. There is a plethora of high high quality properties available at unheard of low prices. Given that Actual Estate is a tangible asset, numerous folks are now looking to move their cash out of the volatile stock market place and into tangibles like gold and genuine estate until the market place stabilizes. Thats very good for Niche Focus Group Bohlke says.

&#13

###

&#13
&#13
&#13
&#13
&#13

A lot more Loan Modification Press Releases

Forensic Mortgage Auditors Expands Audit Focus to Incorporate “Choice Arms” and Reverse Mortgages. Serving Borrowers and Law Firms Nationwide

Posted on by

Miami, FL (PRWEB) December 14, 2009

The proportion of U.S. home owners who owe much more on their mortgages than the properties are worth has swelled to about 23%, threatening prospects for a sustained housing recovery. Practically ten.7 million households had adverse equity in their houses in the third quarter, according to 1st American CoreLogic, a genuine-estate information business primarily based in Santa Ana, Calif.

&#13

A lot more than 40% of borrowers who took out a mortgage in 2006 — when home costs peaked — are under water. Prices have dropped so considerably in some components of the U.S. that some borrowers who took out loans more than five years ago owe more than their home’s value.

&#13

These so-known as underwater mortgages pose a roadblock to a housing recovery because the properties are more probably to fall into bank foreclosure and get dumped into an currently saturated industry. Economists from J.P. Morgan Chase &amp Co. stated Monday they did not anticipate U.S. property rates to hit bottom until early 2011, citing the prospect of oversupply.

&#13

Property rates have fallen so far that 5.three million U.S. households are tied to mortgages that are at least 20% larger than their home’s worth, the Initial American report said. Far more than 520,000 of these borrowers have received a notice of default, according to 1st American.

&#13

Forensic Mortgage Auditors (“FMA”) is a business unit of Professional Witness Solutions, LLC. FMA by way of its staff of experienced mortgage specialists and its information evaluation division, can perform a forensic fact pattern evaluation on a mortgage transaction, moving from the initial application interview all the way through to the closing of the transaction. At every step of the procedure, FMA evaluates the transaction for full complaince with RESPA, TILA, FCRA, HOEPA, and other agency rules and regulations. Every instance of improper practice is identified and FMA will cite to the applicable regulation creating legal assessment less complicated for the borrower’s attorney.

&#13

Report turn-around occasions are rapid, and the reports are usually regarded to be litigation prepared. FMA’s work product can be combined with FRE Report VII qualified expert witness solutions available from FMA’s parent organization.

&#13

FMA provides solutions to Home Owners and Law Firms. If you are an lawyer, or if you or an individual you know is topic to a subprime mortgage, “Option Arm” , or a Reverse Mortgage exactly where concerns of suitability or compliance exist, speak to FMA at (877) 330-9111. Or go to their web internet site at http://www.expert-witness-solutions.com.

&#13

# # #

&#13
&#13
&#13
&#13
&#13

Far more Loan Modification Services Press Releases

Upcoming Meeting to Focus on Management of Invasive Aquatic Weeds

Posted on by


Lawrence, Kansas (PRWEB) June 24, 2013

Scientists, specialists and policymakers interested in the management of aquatic weeds will collect next month for the Aquatic Plant Management Society (APMS) annual meeting. The Weed Science Society of America (WSSA) is amongst the exhibitors at the event, which is scheduled for July 14-17 in San Antonio, Texas.

&#13

The APMS conference has grow to be an essential forum for sharing investigation and best practices that aid us minimize the significant threat aquatic weeds represent to our economy, says Lee Van Wychen, Ph.D., science policy director for the Weed Science Society of America. Aquatic invaders can clog flood handle channels, impair water supplies and endanger essential centers of water-primarily based commerce, recreation and tourism.

&#13

This years APMS conference will function dozens of presentations and poster sessions on invasive aquatic plants and how to best manage them from the use of hydroacoustic technology to track underwater weeds to the newest methods for controlling toxic algae blooms. In addition, 3 unique half-day sessions are planned around the following themes:&#13

&#13

Brookstone Law, Computer, Bank Lending Practice Investigations Focus on Recent Bank of America Revelations

Posted on by


Newport Beach, CA (PRWEB) December 13, 2010

Brookstone Law, Computer, is expanding its civil litigation division and is involved in investigations of the situations all through the nation exactly where actions against buyers have exposed banks unlawful lending practices.

&#13

Among those investigations is assistance for the present high-profile foreclosure case in New Jersey in which a Bank of America spokesperson revealed the Banks unlawful administration of loan documents with subsidiary Countrywide Property Loans. The revelation potentially brings into question the ownership of millions of properties that could lead to Bank of America getting liable for billions of dollars in inherited negative loans.

&#13

In testimony just before the Home Economic Solutions Committees hearings November 17 on Issues in Mortgage Servicing from Modification to Foreclosure, Georgetown University Law Center Professor Adam Levitin described the potentially devastating implications of the case by saying, If these legal troubles are resolved differently, then there would be a failure of the transfer of mortgages into securitization trusts, which would cloud title to nearly each house in the United States and would create contract recession/putback liabilities in the trillions of dollars, tremendously exceeding the capital of the USs key economic institutions.

&#13

The bungled defense by Bank of America in this case is another instance of a trend of rulings against Banks primarily based on a constant lack of legal documentation in mortgage foreclosures, mentioned Vito Torchia, Jr., managing attorney of Brookstone Law. This was a case exactly where the witness told the truth and we all got a appear behind the curtain. Unlawful documentation practices are only one particular of the several obstacles against customers and it is important that these practices are coming to light. The reality that the revelation was by the Banks spokesperson offers it considerable credibility, regardless of the Banks subsequent statements.

&#13

The case is In the Matter of John T. Kemp, Kemp v. Countrywide Residence Loans Inc., 08-02448, U.S. bankruptcy Court for the District of New Jersey (Camden).

&#13

About Brookstone Law, Pc &#13

Primarily based in Los Angeles, with offices in Newport Beach, CA, and Ft. Lauderdale, FL, Brookstone Law, Computer, is a law firm comprised of attorneys with experience and success in business, corporate and personal finance, employment, entertainment &amp media, art &amp museum, intellectual house and true estate law. The firm has a network of a lot more than 40 affiliate attorneys nationwide and employs highly trained specialists, paralegals, paraprofessionals and administrative employees dedicated to serving our consumers. For details, get in touch with (800) 946-8655 or check out http://www.brookstone-law.com.

&#13

# # #

&#13
&#13
&#13
&#13
&#13

More Loan Modification Services Press Releases